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Vertex-wise sulcal depth

ROBO2 · rs35750090

What the study found

Who was studied 33,748 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 15.9 z score higher; p = 9 × 10−57.

How common The C allele had a frequency of about 40% in the people studied.

Where it sits Chromosome 3, band 3p12.3 — in an intron of ROBO2.

What each result means

C/C Two copies of the version the research linked to Vertex-wise sulcal depth. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Vertex-wise sulcal depth. That is a smaller link than two copies.
T/T No copy of the version the research linked to Vertex-wise sulcal depth. This is the starting point the study compared everyone against.
Source

Questions about rs35750090

What is rs35750090?

rs35750090 is a single position in the genome, in or near the ROBO2 gene. Published research associates it with vertex-wise sulcal depth. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs35750090 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35750090 come from?

GWAS Catalog, Science advances 2021, PMID:34910505. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Vertex-wise sulcal depth (rs35750090). MyGeneLog™. https://www.mygenelog.com/variants/rs35750090

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