Sensitive

Basal cell carcinoma

CHMP1A · rs35749174

Where this position leads

Condition: Basal Cell Carcinoma

rs35749174 Condition: Basal Cell Carcinoma Basal Cell Carcinoma Condition rs35749174 rs35749174 CHMP1A

What the study found

Who was studied 17,416 European ancestry cases, 375,455 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.284 higher (95% confidence interval 0.25-0.32); p = 2 × 10−67.

How common The A allele had a frequency of about 10% in the people studied.

Where it sits Chromosome 16, band 16q24.3 — in an intron of CHMP1A.

What each result means

A/A Two copies of the version the research linked to Basal cell carcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Basal cell carcinoma. That is a smaller link than two copies.
G/G No copy of the version the research linked to Basal cell carcinoma. This is the starting point the study compared everyone against.
Source

Questions about rs35749174

What is rs35749174?

rs35749174 is a single position in the genome, in or near the CHMP1A gene. Published research associates it with basal cell carcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs35749174 linked to?

On MyGeneLog this position is linked to Basal Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs35749174 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35749174 come from?

GWAS Catalog, Genome Med 2021, PMID:33549134. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Basal cell carcinoma (rs35749174). MyGeneLog™. https://www.mygenelog.com/variants/rs35749174

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