Standard
Urinary albumin-to-creatinine ratio
AUTS2 · rs35692677
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 547,361 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0164 lower (95% confidence interval 0.011-0.021); p = 3 × 10−10.
How common The A allele had a frequency of about 19% in the people studied.
Where it sits Chromosome 7, band 7q11.22 — in an intron of AUTS2.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Urinary albumin-to-creatinine ratio compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Urinary albumin-to-creatinine ratio.
G/G
Published research associates this genotype with typical/baseline likelihood of Urinary albumin-to-creatinine ratio — no copies of the reported risk allele.
Source
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria
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Li Y,
Ghasemi S,
Prins BP,
Wuttke M,
Hermle T,
Giri A,
Sieber KB,
Qiu C,
Kirsten H,
Tin A,
Chu AY
and 174 more — show all
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Runz H,
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Tai ES,
Tan NYQ,
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Teren A,
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Thio CHL,
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Tönjes A,
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van der Harst P,
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Nature communications · 2019 · PMID 31511532 · open access
Questions about rs35692677
What is rs35692677?
rs35692677 is a single position in the genome, in or near the AUTS2 gene. Published research associates it with urinary albumin-to-creatinine ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs35692677 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs35692677 come from?
GWAS Catalog, Nature communications 2019, PMID:31511532. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Urinary albumin-to-creatinine ratio (rs35692677). MyGeneLog™. https://www.mygenelog.com/variants/rs35692677
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