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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 243,951 European and South Asian ancestry males.
The effect
Each copy of the T allele shifted the measure 0.0241 lower (95% confidence interval 0.016-0.032); p = 7 × 10−10.
How common The T allele had a frequency of about 12% in the people studied.
Where it sits Chromosome 3, band 3p14.2 — in an intron of PTPRG.
What each result means
C/CNo copy of the version the research linked to Testosterone levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Testosterone levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Testosterone levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2025 · PMID 40229599 · open access
Questions about rs35680956
What is rs35680956?
rs35680956 is a single position in the genome, in or near the PTPRG gene. Published research associates it with testosterone levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs35680956 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs35680956 come from?
GWAS Catalog, Nature genetics 2025, PMID:40229599. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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