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Spherical equivalent

GNGT2 · rs35638197

What the study found

Who was studied 95,827 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.18 higher (95% confidence interval 0.14-0.22); p = 6 × 10−15.

Where it sits Chromosome 17, band 17q21.32 — a missense change in GNGT2.

What each result means

C/C No copy of the version the research linked to Spherical equivalent. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Spherical equivalent. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Spherical equivalent. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs35638197

What is rs35638197?

rs35638197 is a single position in the genome, in or near the GNGT2 gene. Published research associates it with spherical equivalent. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs35638197 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35638197 come from?

GWAS Catalog, JAMA ophthalmology 2020, PMID:32352494. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Spherical equivalent (rs35638197). MyGeneLog™. https://www.mygenelog.com/variants/rs35638197

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