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Serum alkaline phosphatase levels

SLC16A11 · rs35634464

What the study found

Who was studied 342,535 European ancestry individuals, 6,019 African ancestry individuals, 7,337 South Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.021 higher (95% confidence interval 0.016-0.026); p = 1 × 10−13.

Where it sits Chromosome 17, band 17p13.1 — in an intron of SLC16A11.

What each result means

A/A Two copies of the version the research linked to Serum alkaline phosphatase levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Serum alkaline phosphatase levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Serum alkaline phosphatase levels. This is the starting point the study compared everyone against.
Source

Questions about rs35634464

What is rs35634464?

rs35634464 is a single position in the genome, in or near the SLC16A11 gene. Published research associates it with serum alkaline phosphatase levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs35634464 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35634464 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Serum alkaline phosphatase levels (rs35634464). MyGeneLog™. https://www.mygenelog.com/variants/rs35634464

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