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Immunoglobulin M levels

FBRS · rs35629860

What the study found

Who was studied 55,368 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0618 SD unit higher (95% confidence interval 0.048-0.075); p = 7 × 10−19.

Where it sits Chromosome 16, band 16p11.2 — in an intron of FBRS.

What each result means

A/A Two copies of the version the research linked to Immunoglobulin M levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Immunoglobulin M levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Immunoglobulin M levels. This is the starting point the study compared everyone against.
Source

Questions about rs35629860

What is rs35629860?

rs35629860 is a single position in the genome, in or near the FBRS gene. Published research associates it with immunoglobulin m levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs35629860 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35629860 come from?

GWAS Catalog, Genes and immunity 2026, PMID:42642615. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Immunoglobulin M levels (rs35629860). MyGeneLog™. https://www.mygenelog.com/variants/rs35629860

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