Tacrolimus trough concentration in kidney transplant patients
CYP3A43 · rs35599367
0 201622216Reads by AI crawlersClaude0ChatGPT0Google · Gemini1Perplexity0Meta AI6Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others6Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 1,345 European ancestry individuals (homozygous for LoF CYPA3A5).
The effect
Each copy of the A allele shifted the measure 0.3 higher (95% confidence interval 0.23-0.37); p = 2 × 10−17.
How common The A allele had a frequency of about 5% in the people studied.
Where it sits Chromosome 7, band 7q22.1 — in an intron of CYP3A4.
What each result means
A/ATwo copies of the version the research linked to Tacrolimus trough concentration in kidney transplant patients. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Tacrolimus trough concentration in kidney transplant patients. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Tacrolimus trough concentration in kidney transplant patients. This is the starting point the study compared everyone against.
The pharmacogenomics journal · 2018 · PMID 29160300
Questions about rs35599367
What is rs35599367?
rs35599367 is a single position in the genome, in or near the CYP3A43 gene. Published research associates it with tacrolimus trough concentration in kidney transplant patients. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs35599367 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs35599367 come from?
GWAS Catalog, Pharmacogenomics J 2017, PMID:29160300. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 201622216Reads by AI crawlersClaude0ChatGPT0Google · Gemini1Perplexity0Meta AI6Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others6Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Tacrolimus trough concentration in kidney transplant patients (rs35599367). MyGeneLog™. https://www.mygenelog.com/variants/rs35599367