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Peak expiratory flow (UKB data field 3064)

near NOTUM · rs35569031

Where this position leads

Condition: Celiac Disease

rs35569031 Condition: Celiac Disease Celiac Disease Condition rs35569031 rs35569031 near NOTUM

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0128 higher (95% confidence interval 0.0091-0.0164); p = 7 × 10−13.

How common The C allele had a frequency of about 65% in the people studied.

Where it sits Chromosome 17, band 17q25.3 — between genes, 0.6 kb from NOTUM.

What each result means

C/C Two copies of the version the research linked to Peak expiratory flow (UKB data field 3064). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Peak expiratory flow (UKB data field 3064). That is a smaller link than two copies.
T/T No copy of the version the research linked to Peak expiratory flow (UKB data field 3064). This is the starting point the study compared everyone against.
Source

Questions about rs35569031

What is rs35569031?

rs35569031 is a single position in the genome, in or near the near NOTUM gene. Published research associates it with peak expiratory flow (ukb data field 3064). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs35569031 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs35569031 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35569031 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Peak expiratory flow (UKB data field 3064) (rs35569031). MyGeneLog™. https://www.mygenelog.com/variants/rs35569031

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