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Triglyceride levels

AXL · rs35538872

What the study found

Who was studied 1,320,016 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0889 lower (95% confidence interval 0.071-0.107); p = 2 × 10−14.

How common The A allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 19, band 19q13.2 — a missense change in AXL.

What ClinVar records

Classification Likely benign for Amenorrhea, Hypogonadotropic hypogonadism 7 with or without anosmia; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 5 submitters), last evaluated 2026-01-22. ClinVar record 785827 NM_021913.5(AXL):c.1549G>A (p.Gly517Ser)

What this is ClinVar's aggregate record for this position (as of its 2026-10-12 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.

What each result means

A/A Two copies of the version the research linked to Triglyceride levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Triglyceride levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Triglyceride levels. This is the starting point the study compared everyone against.
Source

Questions about rs35538872

What is rs35538872?

rs35538872 is a single position in the genome, in or near the AXL gene. Published research associates it with triglyceride levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs35538872 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35538872 come from?

GWAS Catalog, Nature 2021, PMID:34887591. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglyceride levels (rs35538872). MyGeneLog™. https://www.mygenelog.com/variants/rs35538872

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