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Uterine fibroids

near TERT · rs35535053

Where this position leads

Condition: Uterine Fibroids

rs35535053 Condition: Uterine Fibroids Uterine Fibroids Condition rs35535053 rs35535053 near TERT

What the study found

Who was studied 53,711 European ancestry female cases, 380,441 European ancestry female controls.

The effect Each copy of the T allele shifted the measure 0.184 higher (95% confidence interval 0.14-0.22); p = 1 × 10−19.

Where it sits Chromosome 5, band 5p15.33 — between genes, 0.3 kb from TERT.

What each result means

C/C No copy of the version the research linked to Uterine fibroids. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Uterine fibroids. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Uterine fibroids. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs35535053

What is rs35535053?

rs35535053 is a single position in the genome, in or near the near TERT gene. Published research associates it with uterine fibroids. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs35535053 linked to?

On MyGeneLog this position is linked to Uterine Fibroids. The research behind each link, and its sources, are set out on that condition page.

Does having rs35535053 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35535053 come from?

GWAS Catalog, Nature communications 2025, PMID:40050615. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Uterine fibroids (rs35535053). MyGeneLog™. https://www.mygenelog.com/variants/rs35535053

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