Standard
Cognitive performance
CALN1 · rs35526560
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Cognitive performance compared to the general population.
C/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Cognitive performance.
G/G
Published research associates this genotype with typical/baseline likelihood of Cognitive performance — no copies of the reported risk allele.
Source
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
Lee JJ,
Wedow R,
Okbay A,
Kong E,
Maghzian O,
Zacher M,
Nguyen-Viet TA,
Bowers P,
Sidorenko J,
Karlsson Linnér R,
Fontana MA,
Kundu T
and 65 more — show all
Lee C,
Li H,
Li R,
Royer R,
Timshel PN,
Walters RK,
Willoughby EA,
Yengo L,
Alver M,
Bao Y,
Clark DW,
Day FR,
Furlotte NA,
Joshi PK,
Kemper KE,
Kleinman A,
Langenberg C,
Mägi R,
Trampush JW,
Verma SS,
Wu Y,
Lam M,
Zhao JH,
Zheng Z,
Boardman JD,
Campbell H,
Freese J,
Harris KM,
Hayward C,
Herd P,
Kumari M,
Lencz T,
Luan J,
Malhotra AK,
Metspalu A,
Milani L,
Ong KK,
Perry JRB,
Porteous DJ,
Ritchie MD,
Smart MC,
Smith BH,
Tung JY,
Wareham NJ,
Wilson JF,
Beauchamp JP,
Conley DC,
Esko T,
Lehrer SF,
Magnusson PKE,
Oskarsson S,
Pers TH,
Robinson MR,
Thom K,
Watson C,
Chabris CF,
Meyer MN,
Laibson DI,
Yang J,
Johannesson M,
Koellinger PD,
Turley P,
Visscher PM,
Benjamin DJ,
Cesarini D
Nature genetics · 2018 · PMID 30038396
Questions about rs35526560
What is rs35526560?
rs35526560 is a single position in the genome, in or near the CALN1 gene. Published research associates it with cognitive performance. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs35526560 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs35526560 come from?
GWAS Catalog, Nat Genet 2018, PMID:30038396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants