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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 60,225 Chinese ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.166 higher (95% confidence interval 0.12-0.21); p = 6 × 10−12.
How common The C allele had a frequency of about 13% in the people studied.
Where it sits Chromosome 17, band 17q21.2 — between genes, 0.4 kb from ZNF385C.
What each result means
A/ANo copy of the version the research linked to Thyroid peroxidase antibody levels in pregnancy. This is the starting point the study compared everyone against.
A/COne copy of the version the research linked to Thyroid peroxidase antibody levels in pregnancy. That is a smaller link than two copies.
C/CTwo copies of the version the research linked to Thyroid peroxidase antibody levels in pregnancy. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2024 · PMID 39266554 · open access
Questions about rs35490951
What is rs35490951?
rs35490951 is a single position in the genome, in or near the near ZNF385C gene. Published research associates it with thyroid peroxidase antibody levels in pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs35490951 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs35490951 come from?
GWAS Catalog, Nature communications 2024, PMID:39266554. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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Thyroid peroxidase antibody levels in pregnancy (rs35490951). MyGeneLog™. https://www.mygenelog.com/variants/rs35490951