Cryptic phenotype that captures autosomal dominant polycystic kidney disease severity
ARHGAP42 · rs35473622
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 308,095 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.01 lower (95% confidence interval 0.0074-0.0126); p = 8 × 10−13.
Where it sits Chromosome 11, band 11q22.1 — in an intron of ARHGAP42.
What each result means
A/ANo copy of the version the research linked to Cryptic phenotype that captures autosomal dominant polycystic kidney disease severity. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Cryptic phenotype that captures autosomal dominant polycystic kidney disease severity. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Cryptic phenotype that captures autosomal dominant polycystic kidney disease severity. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2022 · PMID 35760791 · open access
Questions about rs35473622
What is rs35473622?
rs35473622 is a single position in the genome, in or near the ARHGAP42 gene. Published research associates it with cryptic phenotype that captures autosomal dominant polycystic kidney disease severity. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs35473622 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs35473622 come from?
GWAS Catalog, Nature communications 2022, PMID:35760791. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 61113Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon1Apple1China (ByteDance, Huawei, Baidu…)0Others3Total6Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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