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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 682 African ancestry cases, 2,540 African ancestry controls, 401 East Asian ancestry cases, 759 East Asian ancestry controls, 13,199 European ancestry cases, 745,011 European ancestry controls, 1,141 South Asian ancestry cases, 5,384 South Asian ancestry controls, 8,779 cases, 1,001,875 controls.
The effect
Each copy of the A allele carried 1.10 times the odds of COVID-19 (critical illness vs population) (95% confidence interval 1.07-1.13); p = 2 × 10−13.
How common The A allele had a frequency of about 32% in the people studied.
Where it sits Chromosome 19, band 19q13.33 — in an intron of NR1H2.
What each result means
A/ATwo copies of the version the research linked to COVID-19 (critical illness vs population). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to COVID-19 (critical illness vs population). That is a smaller link than two copies.
G/GNo copy of the version the research linked to COVID-19 (critical illness vs population). This is the starting point the study compared everyone against.
rs35463555 is a single position in the genome, in or near the NR1H2 gene. Published research associates it with covid-19 (critical illness vs population). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs35463555 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs35463555 come from?
GWAS Catalog, Nature 2023, PMID:37198478. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
COVID-19 (critical illness vs population) (rs35463555). MyGeneLog™. https://www.mygenelog.com/variants/rs35463555