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Skin color

SLC45A2 · rs35414

What the study found

Who was studied 4,985 Iberian ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.161 lower (95% confidence interval 0.13-0.19); p = 2 × 10−21.

How common The T allele had a frequency of about 41% in the people studied.

Where it sits Chromosome 5, band 5p13.2 — in an intron of SLC45A2.

What each result means

C/C No copy of the version the research linked to Skin color. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Skin color. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Skin color. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs35414

What is rs35414?

rs35414 is a single position in the genome, in or near the SLC45A2 gene. Published research associates it with skin color. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs35414 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35414 come from?

GWAS Catalog, Genes 2023, PMID:36672889. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Skin color (rs35414). MyGeneLog™. https://www.mygenelog.com/variants/rs35414

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