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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,020 Korculan or Shetland Isles (founder/genetic isolate) individuals.
The effect
Each copy of the A allele shifted the measure 0.328 lower (95% confidence interval 0.25-0.4); p = 2 × 10−18.
How common The A allele had a frequency of about 24% in the people studied.
Where it sits Chromosome 3, band 3q27.3 — in an intron of ST6GAL1.
What each result means
A/ATwo copies of the version the research linked to Immunoglobulin N-glycan 24 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Immunoglobulin N-glycan 24 levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Immunoglobulin N-glycan 24 levels. This is the starting point the study compared everyone against.
Nature communications · 2022 · PMID 35332118 · open access
Questions about rs35376994
What is rs35376994?
rs35376994 is a single position in the genome, in or near the ST6GAL1 gene. Published research associates it with immunoglobulin n-glycan 24 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs35376994 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs35376994 come from?
GWAS Catalog, Nature communications 2022, PMID:35332118. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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