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Apnea hypopnea index

ZNF277-AS1 · rs35370454

What the study found

Who was studied 3,262 European ancestry individuals, 1,753 African American individuals, 6,381 Hispanic or Latin American individuals, 223 East Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.024 higher (95% confidence interval 0.016-0.032); p = 1 × 10−8.

How common The C allele had a frequency of about 99% in the people studied.

Where it sits Chromosome 7, band 7q31.1 — in an intron of ZNF277-AS1.

What each result means

C/C Two copies of the version the research linked to Apnea hypopnea index. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Apnea hypopnea index. That is a smaller link than two copies.
T/T No copy of the version the research linked to Apnea hypopnea index. This is the starting point the study compared everyone against.
Source

Questions about rs35370454

What is rs35370454?

rs35370454 is a single position in the genome, in or near the ZNF277-AS1 gene. Published research associates it with apnea hypopnea index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs35370454 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35370454 come from?

GWAS Catalog, Sleep 2026, PMID:40736211. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Apnea hypopnea index (rs35370454). MyGeneLog™. https://www.mygenelog.com/variants/rs35370454

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