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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 54,890 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.224 years lower (95% confidence interval 0.18-0.27); p = 1 × 10−25.
How common The A allele had a frequency of about 59% in the people studied.
Where it sits Chromosome 1, band 1q25.3 — in an intron of STX6.
What each result means
A/ATwo copies of the version the research linked to Brain age gap derived from white matter. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Brain age gap derived from white matter. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Brain age gap derived from white matter. This is the starting point the study compared everyone against.
rs35306826 is a single position in the genome, in or near the STX6 gene. Published research associates it with brain age gap derived from white matter. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs35306826 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs35306826 come from?
GWAS Catalog, Nature aging 2025, PMID:41044200. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Brain age gap derived from white matter (rs35306826). MyGeneLog™. https://www.mygenelog.com/variants/rs35306826