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Tenascin protein levels (SomaScan ID:21491-7)

AOC2 · rs35296742

What the study found

Who was studied 199 Shetland Isles origin ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.912 lower (95% confidence interval 0.68-1.14); p = 2 × 10−14.

Where it sits Chromosome 17, band 17q21.31 — in an intron of AOC2.

What each result means

A/A Two copies of the version the research linked to Tenascin protein levels (SomaScan ID:21491-7). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Tenascin protein levels (SomaScan ID:21491-7). That is a smaller link than two copies.
G/G No copy of the version the research linked to Tenascin protein levels (SomaScan ID:21491-7). This is the starting point the study compared everyone against.
Source

Questions about rs35296742

What is rs35296742?

rs35296742 is a single position in the genome, in or near the AOC2 gene. Published research associates it with tenascin protein levels (somascan id:21491-7). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs35296742 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35296742 come from?

GWAS Catalog, Communications biology 2025, PMID:40883583. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Tenascin protein levels (SomaScan ID:21491-7) (rs35296742). MyGeneLog™. https://www.mygenelog.com/variants/rs35296742

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