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Low density lipoprotein cholesterol levels

SARS1 · rs35271870

What the study found

Who was studied 431,167 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.125 higher (95% confidence interval 0.12-0.13); p = 8 × 10−304.

How common The T allele had a frequency of about 91% in the people studied.

Where it sits Chromosome 1, band 1p13.3 — in an intron of SARS1.

What each result means

C/C No copy of the version the research linked to Low density lipoprotein cholesterol levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Low density lipoprotein cholesterol levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Low density lipoprotein cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs35271870

What is rs35271870?

rs35271870 is a single position in the genome, in or near the SARS1 gene. Published research associates it with low density lipoprotein cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs35271870 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35271870 come from?

GWAS Catalog, Diabetes 2020, PMID:32493714. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Low density lipoprotein cholesterol levels (rs35271870). MyGeneLog™. https://www.mygenelog.com/variants/rs35271870

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