Psoriasis or type 2 diabetes (trans-disease meta-analysis)
TCF7L2 · rs35198068
2 443212523224Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity2Meta AI5Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others24Total44Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 11,024 European ancestry psoriasis cases, 74,124 European ancestry diabetes cases, 840,342 European ancestry controls.
The effect
Each copy of the C allele carried 1.18 times the odds of Psoriasis or type 2 diabetes (trans-disease meta-analysis); p = 9 × 10−48.
Where it sits Chromosome 10, band 10q25.2 — in an intron of TCF7L2.
What each result means
C/CTwo copies of the version the research linked to Psoriasis or type 2 diabetes (trans-disease meta-analysis). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Psoriasis or type 2 diabetes (trans-disease meta-analysis). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Psoriasis or type 2 diabetes (trans-disease meta-analysis). This is the starting point the study compared everyone against.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs35198068
What is rs35198068?
rs35198068 is a single position in the genome, in or near the TCF7L2 gene. Published research associates it with psoriasis or type 2 diabetes (trans-disease meta-analysis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs35198068 linked to?
On MyGeneLog this position is linked to Psoriasis. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs35198068?
Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs35198068 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs35198068 come from?
GWAS Catalog, J Invest Dermatol 2020, PMID:33385400. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 443212523224Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity2Meta AI5Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others24Total44Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Psoriasis or type 2 diabetes (trans-disease meta-analysis) (rs35198068). MyGeneLog™. https://www.mygenelog.com/variants/rs35198068