Sensitive

Human papilloma virus 16 negative oropharyngeal cancer

ABTB3 · rs35189640

What the study found

Who was studied 565 European ancestry cases, 5,256 European ancestry controls.

The effect The reported allele is T; the catalogue records no effect size ; p = 1 × 10−9.

Where it sits Chromosome 12, band 12q23.3 — in an intron of ABTB3.

What each result means

C/C No copy of the version the research linked to Human papilloma virus 16 negative oropharyngeal cancer. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Human papilloma virus 16 negative oropharyngeal cancer. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Human papilloma virus 16 negative oropharyngeal cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs35189640

What is rs35189640?

rs35189640 is a single position in the genome, in or near the ABTB3 gene. Published research associates it with human papilloma virus 16 negative oropharyngeal cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs35189640 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35189640 come from?

GWAS Catalog, Nature communications 2021, PMID:34642315. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Human papilloma virus 16 negative oropharyngeal cancer (rs35189640). MyGeneLog™. https://www.mygenelog.com/variants/rs35189640

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