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Facial morphology

SFRP2 · rs35148853

What the study found

Who was studied 10,115 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.124 lower; p = 8 × 10−9.

How common The G allele had a frequency of about 12% in the people studied.

Where it sits Chromosome 4, band 4q31.3 — between genes, 109.3 kb from SFRP2.

What each result means

A/A No copy of the version the research linked to Facial morphology. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Facial morphology. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Facial morphology. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs35148853

What is rs35148853?

rs35148853 is a single position in the genome, in or near the SFRP2 gene. Published research associates it with facial morphology. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs35148853 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35148853 come from?

GWAS Catalog, eLife 2019, PMID:31763980. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Facial morphology (rs35148853). MyGeneLog™. https://www.mygenelog.com/variants/rs35148853

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