Sensitive

Prostate cancer aggressiveness

RASA1 · rs35148638

Where this position leads

Condition: Prostate Cancer

rs35148638 Condition: Prostate Cancer Prostate Cancer Condition rs35148638 rs35148638 RASA1

What the study found

Who was studied 4,545 European ancestry cases; replicated in 7,973 European ancestry cases.

The effect Each copy of the C allele shifted the measure 0.088 higher (95% confidence interval 0.059-0.117); p = 6 × 10−9.

How common The C allele had a frequency of about 26% in the people studied.

Where it sits Chromosome 5, band 5q14.3 — in an intron of RASA1.

What each result means

A/A No copy of the version the research linked to Prostate cancer aggressiveness. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Prostate cancer aggressiveness. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Prostate cancer aggressiveness. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs35148638

What is rs35148638?

rs35148638 is a single position in the genome, in or near the RASA1 gene. Published research associates it with prostate cancer aggressiveness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs35148638 linked to?

On MyGeneLog this position is linked to Prostate Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs35148638 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35148638 come from?

GWAS Catalog, Nat Commun 2015, PMID:25939597. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Prostate cancer aggressiveness (rs35148638). MyGeneLog™. https://www.mygenelog.com/variants/rs35148638

← See all variants