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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 38,372 European or unknown ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0391 higher (95% confidence interval 0.026-0.052); p = 2 × 10−9.
How common The G allele had a frequency of about 65% in the people studied.
Where it sits Chromosome 5, band 5q23.2 — in an intron of PPIC.
What each result means
G/GTwo copies of the version the research linked to Ascending aorta diameter. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to Ascending aorta diameter. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Ascending aorta diameter. This is the starting point the study compared everyone against.
Journal of the American College of Cardiology · 2023 · PMID 37019578
Questions about rs35128692
What is rs35128692?
rs35128692 is a single position in the genome, in or near the PPIC gene. Published research associates it with ascending aorta diameter. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs35128692 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs35128692 come from?
GWAS Catalog, Journal of the American College of Cardiology 2023, PMID:37019578. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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