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Who was studied 67,062 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.654 lower (95% confidence interval 0.45-0.86); p = 3 × 10−10.
How common The T allele had a frequency of about 89% in the people studied.
Where it sits Chromosome 1, band 1q32.2 — in an intron of MIR29B2CHG.
What each result means
C/CNo copy of the version the research linked to Resting heart rate. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Resting heart rate. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Resting heart rate. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2018 · PMID 29769521 · open access
Questions about rs35118522
What is rs35118522?
rs35118522 is a single position in the genome, in or near the CD46 gene. Published research associates it with resting heart rate. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs35118522 linked to?
On MyGeneLog this position is linked to Resting Heart Rate. The research behind each link, and its sources, are set out on that condition page.
Does having rs35118522 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs35118522 come from?
GWAS Catalog, Nature communications 2018, PMID:29769521. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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