Sensitive

diarrhoeal disease at age 1 with doctor diagnosis

FUT2 · rs35106244

Where this position leads

Condition: Diarrhoeal Disease in Infancy

rs35106244 Condition: Diarrhoeal Disease in Infancy Diarrhoeal Disease in Infancy Condition rs35106244 rs35106244 FUT2

What the study found

Who was studied 1,339 European ancestry cases, 5,064 European ancestry controls; replicated in 1,411 European ancestry cases, 6,054 European ancestry controls.

The effect Each copy of the T allele carried 1.27 times the odds of diarrhoeal disease at age 1 with doctor diagnosis (95% confidence interval 1.18-1.35); p = 7 × 10−11.

How common The T allele had a frequency of about 44% in the people studied.

Where it sits Chromosome 19, band 19q13.33 — in an intron of FUT2.

What each result means

C/C No copy of the version the research linked to diarrhoeal disease at age 1 with doctor diagnosis. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to diarrhoeal disease at age 1 with doctor diagnosis. That is a smaller link than two copies.
T/T Two copies of the version the research linked to diarrhoeal disease at age 1 with doctor diagnosis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs35106244

What is rs35106244?

rs35106244 is a single position in the genome, in or near the FUT2 gene. Published research associates it with diarrhoeal disease at age 1 with doctor diagnosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs35106244 linked to?

On MyGeneLog this position is linked to Diarrhoeal Disease in Infancy. The research behind each link, and its sources, are set out on that condition page.

Does having rs35106244 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35106244 come from?

GWAS Catalog, Hum Mol Genet 2016, PMID:27559109. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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diarrhoeal disease at age 1 with doctor diagnosis (rs35106244). MyGeneLog™. https://www.mygenelog.com/variants/rs35106244

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