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TNR protein levels

STAB2 · rs35102665

Where this position leads

Condition: Celiac Disease

rs35102665 Condition: Celiac Disease Celiac Disease Condition rs35102665 rs35102665 STAB2

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.131 higher (95% confidence interval 0.1-0.16); p = 2 × 10−22.

How common The A allele had a frequency of about 3% in the people studied.

Where it sits Chromosome 12, band 12q23.3 — a synonymous change in STAB2.

What each result means

A/A Two copies of the version the research linked to TNR protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to TNR protein levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to TNR protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs35102665

What is rs35102665?

rs35102665 is a single position in the genome, in or near the STAB2 gene. Published research associates it with tnr protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs35102665 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs35102665 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35102665 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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TNR protein levels (rs35102665). MyGeneLog™. https://www.mygenelog.com/variants/rs35102665

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