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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 6,057 European ancestry individuals.
The effect
The reported allele is A; the catalogue records no effect size
; p = 3 × 10−10.
Where it sits Chromosome 9, band 9q31.1 — in an intron of ABCA1.
What each result means
A/ATwo copies of the version the research linked to Trihexosylcermide (d18:1/24:0) levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Trihexosylcermide (d18:1/24:0) levels. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Trihexosylcermide (d18:1/24:0) levels. This is the starting point the study compared everyone against.
Nature communications · 2022 · PMID 35668104 · open access
Questions about rs35093463
What is rs35093463?
rs35093463 is a single position in the genome, in or near the ABCA1 gene. Published research associates it with trihexosylcermide (d18:1/24:0) levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs35093463 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs35093463 come from?
GWAS Catalog, Nature communications 2022, PMID:35668104. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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