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Eosinophil count

D2HGDH · rs35070043

What the study found

Who was studied 365,954 British ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.034 lower (95% confidence interval 0.026-0.042); p = 9 × 10−20.

How common The T allele had a frequency of about 36% in the people studied.

Where it sits Chromosome 2, band 2q37.3 — in an intron of D2HGDH.

What each result means

A/A No copy of the version the research linked to Eosinophil count. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Eosinophil count. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Eosinophil count. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs35070043

What is rs35070043?

rs35070043 is a single position in the genome, in or near the D2HGDH gene. Published research associates it with eosinophil count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs35070043 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35070043 come from?

GWAS Catalog, Frontiers in immunology 2022, PMID:35935937. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Eosinophil count (rs35070043). MyGeneLog™. https://www.mygenelog.com/variants/rs35070043

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