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Who was studied 6,891 European ancestry cases, 54,566 European ancestry controls; replicated in 810 European ancestry cases, 5,600 European ancestry controls.
The effect
Each copy of the T allele carried 1.33 times the odds of Squamous cell carcinoma (95% confidence interval 1.26-1.42); p = 1 × 10−20.
Where it sits Chromosome 16, band 16q24.3 — in the 3′ untranslated region of SPATA33.
What each result means
C/CNo copy of the version the research linked to Squamous cell carcinoma. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Squamous cell carcinoma. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Squamous cell carcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
The Journal of investigative dermatology · 2016 · PMID 26829030
Questions about rs35063026
What is rs35063026?
rs35063026 is a single position in the genome, in or near the SPATA33 gene. Published research associates it with squamous cell carcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs35063026 linked to?
On MyGeneLog this position is linked to Lung Squamous Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs35063026 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs35063026 come from?
GWAS Catalog, The Journal of investigative dermatology 2016, PMID:26829030. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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