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Melanoma

ZNF276 · rs35026726

Where this position leads

Condition: Cutaneous Malignant Melanoma

rs35026726 Condition: Cutaneous Malignant Melanoma Cutaneous Malignant Melanoma Condition rs35026726 rs35026726 ZNF276

What the study found

Who was studied 6,777 European ancestry cases, 410,350 European ancestry controls.

The effect The reported allele is C; the catalogue records no effect size ; p = 4 × 10−61.

Where it sits Chromosome 16, band 16q24.3 — in an intron of ZNF276.

What each result means

C/C Two copies of the version the research linked to Melanoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Melanoma. That is a smaller link than two copies.
T/T No copy of the version the research linked to Melanoma. This is the starting point the study compared everyone against.
Source

Questions about rs35026726

What is rs35026726?

rs35026726 is a single position in the genome, in or near the ZNF276 gene. Published research associates it with melanoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs35026726 linked to?

On MyGeneLog this position is linked to Cutaneous Malignant Melanoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs35026726 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35026726 come from?

GWAS Catalog, Nature communications 2020, PMID:32887889. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Melanoma (rs35026726). MyGeneLog™. https://www.mygenelog.com/variants/rs35026726

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