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White blood cell count

SLC2A1 · rs35022307

Where this position leads

Condition: Blood Cell Counts

rs35022307 Condition: Blood Cell Counts Blood Cell Counts Condition rs35022307 rs35022307 SLC2A1

What the study found

Who was studied 507,850 East Asian ancestry individuals, 420,829 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0145 lower (95% confidence interval 0.011-0.018); p = 3 × 10−15.

Where it sits Chromosome 1, band 1p34.2 — in an intron of SLC2A1.

What ClinVar records

Classification Benign; criteria provided, single submitter (1 of 4 stars, 1 submitter), last evaluated 2021-05-15. ClinVar record 1268514 NM_006516.4(SLC2A1):c.19-428G>A

What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.

What each result means

C/C No copy of the version the research linked to White blood cell count. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to White blood cell count. That is a smaller link than two copies.
T/T Two copies of the version the research linked to White blood cell count. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs35022307

What is rs35022307?

rs35022307 is a single position in the genome, in or near the SLC2A1 gene. Published research associates it with white blood cell count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs35022307 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs35022307 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs35022307 come from?

GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

White blood cell count (rs35022307). MyGeneLog™. https://www.mygenelog.com/variants/rs35022307

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