0 27221812326Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity1Meta AI8Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others6Total27Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 5,201 European ancestry cases, 9,066 European ancestry controls.
The effect
Each copy of the T allele carried 1.83 times the odds of Systemic lupus erythematosus; p = 1 × 10−60.
Where it sits Chromosome 7, band 7q32.1 — in an intron of IRF5.
What each result means
C/CNo copy of the version the research linked to Systemic lupus erythematosus. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Systemic lupus erythematosus. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Systemic lupus erythematosus. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2015 · PMID 26502338 · open access
Questions about rs35000415
What is rs35000415?
rs35000415 is a single position in the genome, in or near the IRF5 gene. Published research associates it with systemic lupus erythematosus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs35000415 linked to?
On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.
Does having rs35000415 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs35000415 come from?
GWAS Catalog, Nat Genet 2015, PMID:26502338. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 27221812326Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity1Meta AI8Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others6Total27Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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