C/CPublished research associates this genotype with typical/baseline likelihood of Systemic lupus erythematosus — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2015, PMID:26502338)
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Systemic lupus erythematosus. (GWAS Catalog, Nat Genet 2015, PMID:26502338)
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Systemic lupus erythematosus compared to the general population. (GWAS Catalog, Nat Genet 2015, PMID:26502338)
rs35000415 is a single position in the genome, in or near the IRF5 gene. Published research associates it with systemic lupus erythematosus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs35000415 linked to?
On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.
Does having rs35000415 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs35000415 come from?
GWAS Catalog, Nat Genet 2015, PMID:26502338. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.