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Who was studied 811,539 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0166 lower (95% confidence interval 0.012-0.021); p = 3 × 10−11.
How common The A allele had a frequency of about 87% in the people studied.
Where it sits Chromosome 4, band 4q32.3 — in an intron of TMEM192.
What each result means
A/ATwo copies of the version the research linked to Highest math class taken (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Highest math class taken (MTAG). That is a smaller link than two copies.
C/CNo copy of the version the research linked to Highest math class taken (MTAG). This is the starting point the study compared everyone against.
rs34995648 is a single position in the genome, in or near the TMEM192 gene. Published research associates it with highest math class taken (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs34995648 linked to?
On MyGeneLog this position is linked to Educational Attainment. The research behind each link, and its sources, are set out on that condition page.
Does having rs34995648 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs34995648 come from?
GWAS Catalog, Nature genetics 2018, PMID:30038396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Highest math class taken (MTAG) (rs34995648). MyGeneLog™. https://www.mygenelog.com/variants/rs34995648