1 361118123118Reads by AI crawlersClaude1ChatGPT0Google · Gemini1Perplexity1Meta AI8Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others18Total36Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 20,373 European ancestry individuals, 2,131 Erasmus Rucphen (founder/genetic isolate) individuals; replicated in 7,302 Asian ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.023 lower (95% confidence interval 0.015-0.031); p = 3 × 10−8.
Where it sits Chromosome 14, band 14q23.1 — between genes, 14.5 kb from SALRNA1.
What each result means
A/ANo copy of the version the research linked to Optic disc area. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Optic disc area. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Optic disc area. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs34935520 is a single position in the genome, in or near the SIX6 gene. Published research associates it with optic disc area. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs34935520 linked to?
On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs34935520 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs34935520 come from?
GWAS Catalog, Hum Mol Genet 2017, PMID:28073927. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 361118123118Reads by AI crawlersClaude1ChatGPT0Google · Gemini1Perplexity1Meta AI8Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others18Total36Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Optic disc area (rs34935520). MyGeneLog™. https://www.mygenelog.com/variants/rs34935520