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Appendicular lean mass

ZBTB4 · rs34914463

What the study found

Who was studied 450,243 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0361 lower (95% confidence interval 0.031-0.041); p = 1 × 10−39.

How common The T allele had a frequency of about 87% in the people studied.

Where it sits Chromosome 17, band 17p13.1 — a missense change in ZBTB4.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Appendicular lean mass — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Appendicular lean mass.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Appendicular lean mass compared to the general population.
Source

Questions about rs34914463

What is rs34914463?

rs34914463 is a single position in the genome, in or near the ZBTB4 gene. Published research associates it with appendicular lean mass. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs34914463 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs34914463 come from?

GWAS Catalog, Commun Biol 2020, PMID:33097823. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Appendicular lean mass (rs34914463). MyGeneLog™. https://www.mygenelog.com/variants/rs34914463

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