Standard

Hashimoto thyroiditis

near RBPJ · rs34897565

Where this position leads

Condition: Lymphocytic Thyroiditis (Hashimoto's)

rs34897565 Condition: Lymphocytic Thyroiditis (Hashimoto's) Lymphocytic Thyroiditis (Hashimoto's) Condition rs34897565 rs34897565 near RBPJ

What the study found

Who was studied 37,850 European, East Asian, African, South Asian, Middle Eastern, Admixed or unknown ancestry cases, 556,334 European, East Asian, African, South Asian, Middle Eastern, Admixed or unknown ancestry controls.

The effect Each copy of the T allele shifted the measure 0.0691 log odds ratio lower (95% confidence interval 0.049-0.09); p = 5 × 10−11.

What each result means

C/C No copy of the version the research linked to Hashimoto thyroiditis. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Hashimoto thyroiditis. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Hashimoto thyroiditis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs34897565

What is rs34897565?

rs34897565 is a single position in the genome, in or near the near RBPJ gene. Published research associates it with hashimoto thyroiditis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs34897565 linked to?

On MyGeneLog this position is linked to Lymphocytic Thyroiditis (Hashimoto's). The research behind each link, and its sources, are set out on that condition page.

Does having rs34897565 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs34897565 come from?

GWAS Catalog, Nature genetics 2026, PMID:42527560. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hashimoto thyroiditis (rs34897565). MyGeneLog™. https://www.mygenelog.com/variants/rs34897565

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