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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 506 European ancestry survivors, 181 European ancestry non-survivors; replicated in 712 European ancestry survivors, 650 European ancestry non-survivors, 411 African American survivors, 290 African American non-survivors.
The effect
Each copy of the T allele carried 1.64 times the odds of Survival in sepsis (95% confidence interval 1.37-6.78); p = 5 × 10−8.
How common The T allele had a frequency of about 2% in the people studied.
Where it sits Chromosome 7, band 7q21.2 — a missense change in SAMD9.
What each result means
C/CNo copy of the version the research linked to Survival in sepsis. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Survival in sepsis. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Survival in sepsis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Critical care (London, England) · 2022 · PMID 36335405 · open access
Questions about rs34896991
What is rs34896991?
rs34896991 is a single position in the genome, in or near the SAMD9 gene. Published research associates it with survival in sepsis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs34896991 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs34896991 come from?
GWAS Catalog, Critical care (London, England) 2022, PMID:36335405. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Survival in sepsis (rs34896991). MyGeneLog™. https://www.mygenelog.com/variants/rs34896991