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Aging

DHX58 · rs34891485

What the study found

Who was studied 1,559,001 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0145 higher (95% confidence interval 0.0099-0.019); p = 5 × 10−10.

Where it sits Chromosome 17, band 17q21.2 — a missense change in DHX58.

What each result means

C/C No copy of the version the research linked to Aging. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Aging. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Aging. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs34891485

What is rs34891485?

rs34891485 is a single position in the genome, in or near the DHX58 gene. Published research associates it with aging. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs34891485 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs34891485 come from?

GWAS Catalog, Nature aging 2023, PMID:37550455. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Aging (rs34891485). MyGeneLog™. https://www.mygenelog.com/variants/rs34891485

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