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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 4,884 European ancestry cases, 434,649 European ancestry controls.
The effect
The reported allele is T; the catalogue records no effect size
; p = 1 × 10−9.
How common The T allele had a frequency of about 48% in the people studied.
Where it sits Chromosome 3, band 3p25.2 — between genes, 4.4 kb from TMEM40.
What each result means
C/CNo copy of the version the research linked to Mitral valve prolapse. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Mitral valve prolapse. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Mitral valve prolapse. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs34871776 is a single position in the genome, in or near the near TMEM40 gene. Published research associates it with mitral valve prolapse. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs34871776 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs34871776 come from?
GWAS Catalog, European heart journal 2022, PMID:35245370. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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