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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 497 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.377 higher (95% confidence interval 0.26-0.5); p = 1 × 10−9.
Where it sits Chromosome 4, band 4p16.3 — in an intron of FGFRL1.
What each result means
C/CTwo copies of the version the research linked to IDUA protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to IDUA protein levels. That is a smaller link than two copies.
T/TNo copy of the version the research linked to IDUA protein levels. This is the starting point the study compared everyone against.
Scientific reports · 2024 · PMID 38565889 · open access
Questions about rs34869253
What is rs34869253?
rs34869253 is a single position in the genome, in or near the FGFRL1 gene. Published research associates it with idua protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs34869253 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs34869253 come from?
GWAS Catalog, Scientific reports 2024, PMID:38565889. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
IDUA protein levels (rs34869253). MyGeneLog™. https://www.mygenelog.com/variants/rs34869253