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Age at first sexual intercourse

HSD17B12 · rs34804222

Where this position leads

Condition: Age at First Sexual Intercourse

rs34804222 Condition: Age at First Sexual Intercourse Age at First Sexual Intercourse Condition rs34804222 rs34804222 HSD17B12

What the study found

Who was studied 397,338 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0151 lower (95% confidence interval 0.011-0.019); p = 2 × 10−13.

How common The A allele had a frequency of about 59% in the people studied.

Where it sits Chromosome 11, band 11p11.2 — in an intron of HSD17B12.

What each result means

A/A Two copies of the version the research linked to Age at first sexual intercourse. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Age at first sexual intercourse. That is a smaller link than two copies.
G/G No copy of the version the research linked to Age at first sexual intercourse. This is the starting point the study compared everyone against.
Source

Questions about rs34804222

What is rs34804222?

rs34804222 is a single position in the genome, in or near the HSD17B12 gene. Published research associates it with age at first sexual intercourse. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs34804222 linked to?

On MyGeneLog this position is linked to Age at First Sexual Intercourse. The research behind each link, and its sources, are set out on that condition page.

Does having rs34804222 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs34804222 come from?

GWAS Catalog, Nature human behaviour 2021, PMID:34211149. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Age at first sexual intercourse (rs34804222). MyGeneLog™. https://www.mygenelog.com/variants/rs34804222

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