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Sleep duration

UBL5 · rs34786000

Where this position leads

Condition: Sleep and Circadian Rhythm

rs34786000 Condition: Sleep and Circadian Rhythm Sleep and Circadian Rhythm Condition rs34786000 rs34786000 UBL5

What the study found

Who was studied 91,105 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0279 SD units lower (95% confidence interval 0.019-0.037); p = 3 × 10−9.

How common The G allele had a frequency of about 45% in the people studied.

Where it sits Chromosome 19, band 19p13.2 — in an intron of PIN1-DT.

What each result means

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Sleep duration compared to the general population.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Sleep duration.
T/T Published research associates this genotype with typical/baseline likelihood of Sleep duration — no copies of the reported risk allele.
Source

Questions about rs34786000

What is rs34786000?

rs34786000 is a single position in the genome, in or near the UBL5 gene. Published research associates it with sleep duration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs34786000 linked to?

On MyGeneLog this position is linked to Sleep and Circadian Rhythm. The research behind each link, and its sources, are set out on that condition page.

Does having rs34786000 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs34786000 come from?

GWAS Catalog, Nat Commun 2018, PMID:30531941. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Sleep duration (rs34786000). MyGeneLog™. https://www.mygenelog.com/variants/rs34786000

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