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Body mass index (change over time)

NOS1AP · rs347313

Where this position leads

Condition: Obesity and Body Weight

Drug: QT-prolonging medicines

rs347313 Condition: Obesity and Body Weight Obesity and Body Weight Condition Drug: QT-prolonging medicines QT-prolonging medicines Drug rs347313 rs347313 NOS1AP

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Body mass index (change over time) — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Body mass index (change over time).
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Body mass index (change over time) compared to the general population.
Source

Questions about rs347313

What is rs347313?

rs347313 is a single position in the genome, in or near the NOS1AP gene. Published research associates it with body mass index (change over time). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs347313 linked to?

On MyGeneLog this position is linked to Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.

Does rs347313 affect how medicines work?

NOS1AP carries pharmacogenomic findings for QT-prolonging medicines. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.

Does having rs347313 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs347313 come from?

GWAS Catalog, PLoS One 2014, PMID:25133637. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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