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The effect
Each copy of the T allele carried 1.09 times the odds of Chronic obstructive pulmonary disease (95% confidence interval 1.06-1.12); p = 1 × 10−8.
How common The T allele had a frequency of about 14% in the people studied.
Where it sits Chromosome 17, band 17q12 — between genes, 3.9 kb from EPOP.
What each result means
C/CNo copy of the version the research linked to Chronic obstructive pulmonary disease. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Chronic obstructive pulmonary disease. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Chronic obstructive pulmonary disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2019 · PMID 30804561 · open access
Questions about rs34727469
What is rs34727469?
rs34727469 is a single position in the genome, in or near the RPL23 gene. Published research associates it with chronic obstructive pulmonary disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs34727469 linked to?
On MyGeneLog this position is linked to Chronic Obstructive Pulmonary Disease (COPD). The research behind each link, and its sources, are set out on that condition page.
Does having rs34727469 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs34727469 come from?
GWAS Catalog, Nature genetics 2019, PMID:30804561. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 312Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total3Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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