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Triglycerides in large LDL

near APOB · rs34722314

What the study found

Who was studied 98,316 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.00352 lower (95% confidence interval 0.003-0.004); p = 4 × 10−43.

How common The A allele had a frequency of about 13% in the people studied.

Where it sits Chromosome 2, band 2p24.1 — between genes, 4.8 kb from APOB.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Triglycerides in large LDL compared to the general population.
A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Triglycerides in large LDL.
T/T Published research associates this genotype with typical/baseline likelihood of Triglycerides in large LDL — no copies of the reported risk allele.
Source

Questions about rs34722314

What is rs34722314?

rs34722314 is a single position in the genome, in or near the near APOB gene. Published research associates it with triglycerides in large ldl. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs34722314 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs34722314 come from?

GWAS Catalog, Ophthalmology science 2024, PMID:39091897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglycerides in large LDL (rs34722314). MyGeneLog™. https://www.mygenelog.com/variants/rs34722314

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