0 110Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total1Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 5 Hutterite (founder/genetic isolate) cases, 26 Hutterite (founder/genetic isolate) controls.
The effect
Each copy of the A allele carried 2.43 times the odds of Alzheimer's disease (95% confidence interval 1.98-2.98); p = 1 × 10−10.
Where it sits Chromosome 4, band 4q25 — in an intron of LEF1-AS1.
What each result means
A/ATwo copies of the version the research linked to Alzheimer's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Alzheimer's disease. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Alzheimer's disease. This is the starting point the study compared everyone against.
Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023 · PMID 35770850
Questions about rs34710518
What is rs34710518?
rs34710518 is a single position in the genome, in or near the LEF1-AS1 gene. Published research associates it with alzheimer's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs34710518 linked to?
On MyGeneLog this position is linked to Alzheimer's Disease Risk (APOE). The research behind each link, and its sources, are set out on that condition page.
Does having rs34710518 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs34710518 come from?
GWAS Catalog, Alzheimer's & dementia : the journal of the Alzheimer's Association 2023, PMID:35770850. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 110Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total1Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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