0 31112185238Reads by AI crawlersClaude1ChatGPT1Google · Gemini2Perplexity1Meta AI8Microsoft · Copilot5Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others8Total31Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 171,643 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0644 lower (95% confidence interval 0.045-0.084); p = 9 × 10−11.
How common The A allele had a frequency of about 3% in the people studied.
Where it sits Chromosome 8, band 8p11.21 — a missense change in ANK1.
What ClinVar records
ClassificationBenign/Likely benign for Hereditary spherocytosis type 1, Spherocytosis, Thyroid cancer, nonmedullary, 1, Melanoma, Acute myeloid leukemia and 9 more; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 9 submitters), last evaluated 2026-02-01.
ClinVar record 261310NM_000037.4(ANK1):c.4385C>T (p.Ala1462Val)
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
A/ATwo copies of the version the research linked to Lymphocyte count. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Lymphocyte count. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Lymphocyte count. This is the starting point the study compared everyone against.
rs34664882 is a single position in the genome, in or near the ANK1 gene. Published research associates it with lymphocyte count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs34664882 linked to?
On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.
Does having rs34664882 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs34664882 come from?
GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 31112185238Reads by AI crawlersClaude1ChatGPT1Google · Gemini2Perplexity1Meta AI8Microsoft · Copilot5Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others8Total31Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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